Unless you have specialized in biology most people understand antibody as a biological term. In simpler terms antibodies are immunoglobulin produced by white blood cells. Antibodies are large and Y shaped and their role in the immune system is to respond to the presence of disease causing organisms in the body. The moment a threat to the well-being of the body enters the body the immune system starts to act against it. Disease causing organisms are either chemicals, viruses and bacteria. The immune system responds to antigens by producing antibodies that will mark them after that the immune system will destroy the marked threat. It is right to picture antibodies as scouts which are sent throughout the body to mark the antigen by sticking to it and the immune system can conveniently destroy it.
Each antibody is made for a specific antigen and it bears receptors that are specially going to bond with that antigen. Once the antigen has been attacked and rid of the body, the antibody is still retained in the body to await any future attacks from the same antigen. In the event that the same antigen attacks the body the process of dealing with the antigen will be much quicker than the precious time. Immunizations are weak antigens that are not strong to make the body sick, they however sufficient to trigger the production antibodies. Antibodies are of five types and they are found in different areas of the body.
Manipulation of systems of organisms is nothing new in this era where medicine advancement is at an all-time high. Immunohistochemistry combines the use of immunological , biochemical and anatomical means to image the components that are highly discrete in the tissue by using antibodies that have been labeled to stick to the antigen. Here the antigen is targeted and specific and hence the need to label the antibody.
IHC Immunohistochemistry has several applications, its used in drug development , in research and developing drugs. When performing tests for presence of tumors in the body androgen markers are used in IHC, this is one very effective way. IHC is used as a confirmation diagnosis or I could be used as primary diagnosis especially when the patient has been advised to have it for the first time. When it comes to research IHC can be used alone or it could be used in conjunction with other procedures of analysis. Immunohistochemistry in drug development monitors activity and efficacy of the drug by the aid of disease markers in target tissue.